Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787046 | 0.78 | KDM4E (0.43) | KDM4EMEN1MAPTKMT2ATHRB | |
| SCHEMBL6049113 | 0.78 | KDM4E (0.48) | KDM4EMEN1MAPTKMT2ATHRB | |
| SCHEMBL29566358 | 0.78 | KDM4E (0.43) | KDM4EMEN1MAPTKMT2ATHRB | |
| SCHEMBL29793907 | 0.78 | KDM4E (0.43) | KDM4EMEN1MAPTKMT2ATHRB | |
| SCHEMBL526630 | 0.77 | IDO1 (0.56) | KDM4EMEN1MAPTKMT2ATHRB | |
| SCHEMBL5974819 | 0.76 | KDM4E (0.41) | KDM4EMEN1MAPTKMT2ATHRB | |
| SCHEMBL5974811 | 0.76 | KDM4E (0.41) | KDM4EMEN1MAPTKMT2ATHRB | |
| SCHEMBL7206760 | 0.74 | IDO1 (0.53) | KDM4EMEN1MAPTKMT2ATHRB | |
| SCHEMBL888293 | 0.74 | PADI4 (0.55) | KDM4EMEN1MAPTKMT2ATHRB | |
| SCHEMBL29648165 | 0.74 | IDO1 (0.53) | KDM4EMEN1MAPTKMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230149562-A1 | CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY | TIBA BIOTECH LLC (US) | 2023-05-18 | — | — | US | claimed |
| EP-4132586-A1 | CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY | Tiba Biotech LLC (US) | 2023-02-15 | — | — | EP | claimed |
| CN-115702005-A | Vectors for efficient nucleic acid delivery | 蒂巴生物技术有限公司 | 2023-02-14 | — | — | CN | claimed |
| US-20230149562-A1 | CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY | TIBA BIOTECH LLC (US) | 2023-05-18 | — | — | US | disclosed |
| EP-4132586-A1 | CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY | Tiba Biotech LLC (US) | 2023-02-15 | — | — | EP | disclosed |
| CN-115702005-A | Vectors for efficient nucleic acid delivery | 蒂巴生物技术有限公司 | 2023-02-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230149562-A1 | CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY | POLN, TLR9, TSG101 | KDM4E 4832/4885MEN1 2899/4885MAPT 2985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.