Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23723741 | 1.00 | ALDH1A1 (0.50) | ALDH1A1NPSR1ALPLPOLBMAPK1 | |
| SCHEMBL30132048 | 0.94 | ALDH1A1 (0.49) | ALDH1A1NPSR1ALPLPOLBMAPK1 | |
| SCHEMBL23723595 | 0.94 | ALDH1A1 (0.49) | ALDH1A1NPSR1ALPLPOLBMAPK1 | |
| SCHEMBL30120683 | 0.93 | ALDH1A1 (0.43) | ALDH1A1NPSR1ALPLPOLBMAPK1 | |
| SCHEMBL26521628 | 0.93 | ALDH1A1 (0.43) | ALDH1A1NPSR1ALPLPOLBMAPK1 | |
| SCHEMBL23723504 | 0.91 | ALDH1A1 (0.54) | ALDH1A1NPSR1ALPLPOLBMAPK1 | |
| SCHEMBL30132113 | 0.91 | ALDH1A1 (0.54) | ALDH1A1NPSR1ALPLPOLBMAPK1 | |
| SCHEMBL23723611 | 0.90 | KMT2A (0.49) | ALDH1A1NPSR1ALPLPOLBMAPK1 | |
| SCHEMBL30120732 | 0.90 | KMT2A (0.49) | ALDH1A1NPSR1ALPLPOLBMAPK1 | |
| SCHEMBL23723503 | 0.86 | ALDH1A1 (0.42) | ALDH1A1NPSR1ALPLPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100015-A1 | COMBINATION THERAPY FOR TREATING MPS1 | Gain Therapeutics SA (CH) | 2022-12-14 | — | — | EP | disclosed |