Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20554321 | 1.00 | MAPT (0.35) | MAPTKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL30132559 | 0.85 | MAPT (0.36) | MAPTKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL20554534 | 0.85 | MAPT (0.36) | MAPTKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL20554267 | 0.85 | HTR2A (0.33) | HPGDKMT2ASLC6A4HTR2AHTR2C | |
| SCHEMBL30132527 | 0.85 | HTR2A (0.33) | HPGDKMT2ASLC6A4HTR2AHTR2C | |
| SCHEMBL20554109 | 0.85 | L3MBTL1 (0.41) | MAPTKDM4ESLC6A4HTR2AKCNH2 | |
| SCHEMBL30132635 | 0.82 | MAPT (0.36) | MAPTKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL20554374 | 0.82 | MAPT (0.36) | MAPTKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL20554813 | 0.78 | ALOX5AP (0.39) | — | |
| SCHEMBL20554695 | 0.76 | PTGDR2 (0.35) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-108430972-B | Alpha, beta-unsaturated amide compound | 协和麒麟株式会社 | 2022-12-27 | — | — | CN | disclosed |