Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 16/20 | 0.61 |
| ▸ | GRM5 | P41594 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20554464 | 1.00 | MAOB (0.61) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL11386241 | 0.80 | MAOB (0.67) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL28232982 | 0.80 | MAOA (0.55) | MAOBMAOAPARP15PARP10 | |
| SCHEMBL27894160 | 0.79 | MAOB (0.70) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL13264507 | 0.78 | MAOB (0.70) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL14162499 | 0.78 | MAOB (0.64) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL7649580 | 0.78 | MAOA (0.56) | MAOBMAOAPARP15PARP10 | |
| Cyclopropane SCHEMBL28516873 | 0.77 | MAOB (0.59) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL10461501 | 0.77 | MAOB (0.69) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL13506182 | 0.77 | MAOB (0.63) | MAOBGRM5NPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-108430972-B | Alpha, beta-unsaturated amide compound | 协和麒麟株式会社 | 2022-12-27 | — | — | CN | disclosed |