Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20554071 | 1.00 | TRPV1 (0.35) | TRPV1SCN9AKCNH2SCN5AL3MBTL1 | |
| SCHEMBL30132647 | 0.83 | HTT (0.37) | HTR1ADRD2DRD1HTR1BHTR2A | |
| SCHEMBL20554767 | 0.83 | HTT (0.37) | HTR1ADRD2DRD1HTR1BHTR2A | |
| SCHEMBL20554318 | 0.80 | DRD2 (0.41) | TRPV1SCN9AL3MBTL1RAB9ADRD2 | |
| SCHEMBL19054515 | 0.75 | TEAD1 (0.50) | SCN9AKCNH2SCN5AMTNR1A | |
| SCHEMBL30132586 | 0.75 | TEAD1 (0.50) | SCN9AKCNH2SCN5AMTNR1A | |
| SCHEMBL873501 | 0.74 | DRD2 (0.54) | HTR1ADRD2DRD1HTR1BHTR2A | |
| SCHEMBL4839911 | 0.74 | DRD2 (0.54) | HTR1ADRD2DRD1HTR1BHTR2A | |
| SCHEMBL873500 | 0.74 | DRD2 (0.54) | HTR1ADRD2DRD1HTR1BHTR2A | |
| SCHEMBL19667511 | 0.68 | KDM1A (0.44) | L3MBTL1HTR1AHTR2CLTA4HMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-108430972-B | Alpha, beta-unsaturated amide compound | 协和麒麟株式会社 | 2022-12-27 | — | — | CN | disclosed |