Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 7/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1356433 | 1.00 | CYP11B1 (0.43) | CYP11B1CYP11B2POLBHCAR2CYP2A6 | |
| SCHEMBL12133934 | 0.79 | CYP11B1 (0.60) | CYP11B1CYP11B2CYP2A6RAB9A | |
| SCHEMBL748571 | 0.78 | CHRNB2 (0.34) | POLBHCAR2CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL744158 | 0.78 | TSHR (0.37) | POLBHCAR2CYP2A6CHRNB2CHRNA4 | |
| SCHEMBL23352226 | 0.78 | CYP11B1 (0.51) | CYP11B1CYP11B2HCAR2 | |
| SCHEMBL30858980 | 0.77 | POLB (0.30) | POLBHCAR2 | |
| SCHEMBL3564666 | 0.76 | CCNB2 (0.31) | — | |
| SCHEMBL13912176 | 0.76 | CYP11B1 (0.43) | CYP11B1CYP11B2 | |
| SCHEMBL4073597 | 0.76 | CYP11B1 (0.43) | CYP11B1CYP11B2KDM4E | |
| SCHEMBL31407244 | 0.73 | SMYD3 (0.35) | POLBHCAR2CYP2A6CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321044-A | Poly (ADP-ribose) polymerase inhibitors | 理森制药股份公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-115485271-A | Novel compounds as inhibitors of poly (ADP-ribose) polymerase (PARP) | 理森制药股份公司 | 2022-12-16 | — | — | CN | disclosed |