Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2825274 | 1.00 | USP30 (0.50) | USP30NR1H2NOTUMKDM1AEGFR | |
| SCHEMBL2363147 | 0.90 | NR1H2 (0.46) | USP30NR1H2NOTUMKDM1AEGFR | |
| SCHEMBL3897500 | 0.86 | USP30 (0.51) | USP30NOTUMKDM1AEGFRBTK | |
| SCHEMBL26429611 | 0.86 | USP30 (0.51) | USP30NOTUMKDRMAPTMEN1 | |
| SCHEMBL8131708 | 0.85 | MAPT (0.45) | USP30NOTUMKDRMAPTMEN1 | |
| SCHEMBL5276056 | 0.85 | USP30 (0.50) | USP30NOTUMKDM1AEGFRBTK | |
| SCHEMBL26092853 | 0.82 | USP30 (0.48) | USP30NOTUMKDM1AEGFRBTK | |
| SCHEMBL30419049 | 0.82 | USP30 (0.48) | USP30NOTUMKDM1AEGFRBTK | |
| SCHEMBL26429621 | 0.81 | HDAC1 (0.50) | USP30NOTUMEGFRBTKCSNK2A1 | |
| SCHEMBL29628537 | 0.81 | NOTUM (0.64) | USP30NOTUMKDM1AMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025201477-A1 | SPIROCYCLIC GSDME INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO.,LTD. (CN) | 2025-10-02 | — | — | WO | disclosed |
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-11 | — | — | US | disclosed |
| EP-4117640-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | The Regents of the University of California (US) | 2023-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | FEM1B, GSKIP, FNIP1 | USP30 1756/4885NR1H2 2284/4885NOTUM 4098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.