Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 6/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | FYN | P06241 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258647 | 0.80 | CYP2E1 (0.57) | CYP2C9CYP2E1CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL10985144 | 0.79 | CYP2E1 (0.51) | HSD17B1HSD17B2CYP2C9CYP2E1CYP2A6 | |
| SCHEMBL311156 | 0.79 | CYP2E1 (0.65) | CYP2C9CYP2E1CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL23539461 | 0.79 | CYP2E1 (0.56) | CYP2C9CYP2E1CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL30042352 | 0.79 | CYP2E1 (0.56) | CYP2C9CYP2E1CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL9657296 | 0.79 | CYP2E1 (0.56) | CYP2C9CYP2E1CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL3919604 | 0.79 | CYP2E1 (0.56) | CYP2C9CYP2E1CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL21566689 | 0.76 | CYP2E1 (0.53) | CYP2C9CYP2E1CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL17300882 | 0.76 | CYP2E1 (0.53) | CYP2C9CYP2E1CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL17304016 | 0.76 | CYP2E1 (0.53) | CYP2C9CYP2E1CYP2A6CYP2B6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605596-A | Compositions and methods for inducible alternative splicing modulation of gene expression | 费城儿童医院（US） | 2023-01-13 | — | — | CN | disclosed |