SCHEMBL311156

SCHEMBL311156

Cn1cnc(-c2ccccc2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2E1 P05181 1/20 0.65
CYP2A6 P11509 1/20 0.65
CYP2C9 P11712 1/20 0.65
CYP2B6 P20813 1/20 0.65
CYP2C19 P33261 1/20 0.65
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
NLRP3 Q96P20 1/20 0.49
KMT2A Q03164 3/20 0.47
FTO Q9C0B1 1/20 0.47
HRH4 Q9H3N8 1/20 0.45
CSF1R P07333 1/20 0.43
PLK4 O00444 1/20 0.42
JAK2 O60674 1/20 0.42
RET P07949 1/20 0.42
PIM1 P11309 1/20 0.42
FGFR1 P11362 1/20 0.42
FLT1 P17948 1/20 0.42
KDR P35968 1/20 0.42
FLT3 P36888 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2314169 0.85 HPGDS (0.59) CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19
SCHEMBL8818815 0.83 CYP2C9 (0.53) CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19
SCHEMBL18806853 0.81 CYP2C9 (0.57) CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19
SCHEMBL12427187 0.81 CYP2E1 (0.62) CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19
SCHEMBL8250569 0.81 LRRK2 (0.59) CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19
SCHEMBL8258647 0.80 CYP2E1 (0.57) CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19
SCHEMBL746841 0.79 CYP2C9 (0.51) CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19
SCHEMBL12427197 0.79 CYP2E1 (0.51) CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19
SCHEMBL2671981 0.79 CYP2C9 (0.51) CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19
SCHEMBL10985144 0.79 CYP2E1 (0.51) CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 368 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577243-B2 Monoacylglycerol lipase modulators JANSSEN PHARMACEUTICA NV (BE) 2026-03-17 US disclosed
EP-4584259-A1 CK1ALPHA AND DUAL CK1ALPHA / GSPT1 DEGRADING COMPOUNDS Innovo Therapeutics, Inc. (US) 2025-07-16 EP disclosed
CN-119306753-A Methods for preparing JAK inhibitors and related intermediate compounds 因西特控股公司 2025-01-14 CN disclosed
US-20240239801-A1 PYRIMIDO[5,4,D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF Université de Montréal (CA) 2024-07-18 US disclosed
US-20240239801-A1 PYRIMIDO[5,4,D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF Université de Montréal (CA) 2024-07-18 US disclosed
US-20240217971-A1 PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE Université de Montréal (CA) 2024-07-04 US disclosed
WO-2024133292-A1 NOVEL CCR8 ANTAGONISTS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2024-06-27 WO disclosed
US-20240158370-A1 CK1 alpha AND DUAL CK1 alpha / GSPT1 DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. 2024-05-16 US disclosed
WO-2024077391-A1 THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF UNIVERSITE DE MONTREAL (CA) 2024-04-18 WO disclosed
WO-2024054832-A1 CK1α AND DUAL CK1α / GSPT1 DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. (US) 2024-03-14 WO disclosed
US-4493889-A RED SENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 1985-01-15 US disclosed
US-4105454-A BENZOTRIAZOLE COMPOUND WHICH CAN PRODUCE SLIGHTLY SOLUBLE SILVER SALT FUJI PHOTO FILM CO., LTD. (JP) 1978-08-08 US disclosed
US-4097284-A TRIMETHINECYANINE DYE AND A NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING A MERCAPTO FUJI PHOTO FILM CO., LTD. (JA) 1978-06-27 US disclosed
US-4046572-A SILVER HALIDE PHOTOGRAPHIC LIGHT SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JA) 1977-09-06 US disclosed
US-4030927-A PHOTOGRAPHIC SILVER HALIDE EMULSIONS FUJI PHOTO FILM CO., LTD. (JA) 1977-06-21 US disclosed
US-4002480-A CONTAINING A DINUCLEAR MEROCYANINE SENSITIZING DYE AND AN ANTIFOGGING AGENT FUJI PHOTO FILM CO., LTD. (JA) 1977-01-11 US disclosed
US-3994733-A CYANINE DYES, A BENZOTHIAZOLE, OR BENZOTHIAZOLONE, OR NAPHTHOTHIAZOLE, OR NAPHTHOTHIAZOLONE, OR A QUINOLONE FUJI PHOTO FILM CO., LTD. (JA) 1976-11-30 US disclosed
US-3953215-A X-RAY FILM FUJI PHOTO FILM CO., LTD. (JA) 1976-04-27 US disclosed
US-3951666-A CYANINE AND MEROCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-04-20 US disclosed
US-3945832-A Fogged, direct-positive silver halide emulsion containing desensitizers and a dimethine optical sensitizing dye FUJI PHOTO FILM CO., LTD. (JA) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577243-B2 Monoacylglycerol lipase modulators MGLL, LPL, FAAH CYP2E1 316/4885CYP2A6 555/4885CYP2C9 694/4885
US-20240158370-A1 CK1 alpha AND DUAL CK1 alpha / GSPT1 DEGRADING COMPOUNDS CKS1B, CKS2, MARK1 CYP2E1 2776/4885CYP2A6 3490/4885CYP2C9 4284/4885
US-20240239801-A1 PYRIMIDO[5,4,D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF NRAS, BRAF, KRAS CYP2E1 2613/4885CYP2A6 2110/4885CYP2C9 2402/4885
US-20240217971-A1 PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE BRAF, NRAS, DPYD CYP2E1 2717/4885CYP2A6 1874/4885CYP2C9 3114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.