Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.40 |
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25339334 | 0.80 | SLC6A4 (0.51) | HTR1DSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2020517 | 0.79 | ESR2 (0.59) | ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL1628438 | 0.78 | BACE1 (0.49) | SLC6A2SLC6A4SLC6A3ESR2ESR1 | |
| SCHEMBL7809070 | 0.77 | OPRL1 (0.61) | OPRL1PIK3CDPIK3CA | |
| SCHEMBL29991729 | 0.77 | BACE1 (0.51) | SLC6A2SLC6A4SLC6A3ESR2ESR1 | |
| SCHEMBL2698584 | 0.77 | BACE1 (0.51) | SLC6A2SLC6A4SLC6A3ESR2ESR1 | |
| SCHEMBL7968419 | 0.74 | QDPR (0.61) | SLC6A2SLC6A4SLC6A3ESR2ESR1 | |
| SCHEMBL30824511 | 0.73 | IKBKB (0.41) | HTR1D | |
| SCHEMBL6399792 | 0.71 | SLC6A4 (0.43) | SLC6A2SLC6A4SLC6A3ESR2ESR1 | |
| SCHEMBL31063246 | 0.70 | QDPR (0.43) | HTR1DOPRL1ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605596-A | Compositions and methods for inducible alternative splicing modulation of gene expression | 费城儿童医院（US） | 2023-01-13 | — | — | CN | disclosed |