Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.61 |
| ▸ | NOS2 | P35228 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 6/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.30 |
| ▸ | NCF1 | P14598 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23860983 | 1.00 | NOS3 (0.61) | NOS3NOS2HTR6NUDT1ALOX15 | |
| SCHEMBL4113732 | 0.80 | NOS3 (0.39) | NOS3NOS2HTR6ALDH1A1KDM4E | |
| SCHEMBL1821173 | 0.77 | — | — | |
| SCHEMBL26130111 | 0.77 | NOS3 (0.36) | NOS3NOS2ALOX15ALDH1A1KDM4E | |
| SCHEMBL943294 | 0.76 | NOS3 (1.00) | NOS3NOS2ALOX15ALDH1A1KDM4E | |
| SCHEMBL13727358 | 0.75 | LCK (0.46) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5789884 | 0.74 | NOS3 (0.41) | NOS3NOS2HTR6NUDT1ALOX15 | |
| Hydrochloric Acid SCHEMBL28377173 | 0.74 | NOS3 (0.95) | NOS3NOS2ALOX15ALDH1A1KDM4E | |
| SCHEMBL17707988 | 0.74 | NOS3 (0.57) | NOS3NOS2NUDT1ALOX15ALDH1A1 | |
| SCHEMBL25336171 | 0.74 | NOS3 (0.57) | NOS3NOS2NUDT1ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605466-B | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-115605466-A | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司（US） | 2023-01-13 | — | — | CN | disclosed |