Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23860977 | 1.00 | KMT2A (0.45) | KMT2AMEN1CYP3A4KDM4ECYP1A2 | |
| SCHEMBL23860926 | 0.82 | MEN1 (0.41) | KMT2AMEN1NR1H3ARALPL | |
| SCHEMBL30133449 | 0.82 | MEN1 (0.41) | KMT2AMEN1NR1H3ARALPL | |
| SCHEMBL3641427 | 0.75 | MEN1 (0.45) | KMT2AMEN1CYP3A4KDM4ECYP1A2 | |
| SCHEMBL30133451 | 0.74 | MEN1 (0.37) | KMT2AMEN1CYP3A4MAPTNFKB1 | |
| SCHEMBL23861034 | 0.74 | MEN1 (0.37) | KMT2AMEN1CYP3A4MAPTNFKB1 | |
| SCHEMBL23860829 | 0.72 | MEN1 (0.45) | KMT2AMEN1KDM4ENR1H2NR1H3 | |
| SCHEMBL9837203 | 0.70 | RXFP1 (0.38) | KMT2AMEN1MAPTARALPL | |
| SCHEMBL27510936 | 0.69 | MEN1 (0.49) | KMT2AMEN1KDM4EMAPTHPGD | |
| SCHEMBL893875 | 0.69 | MEN1 (0.44) | KMT2AMEN1CYP3A4KDM4ENFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605466-B | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-115605466-A | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司（US） | 2023-01-13 | — | — | CN | disclosed |