Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23860926 | 1.00 | MEN1 (0.41) | MEN1KMT2ASCN2AALPLAR | |
| SCHEMBL23860977 | 0.82 | KMT2A (0.45) | MEN1KMT2AALPLARNR1H3 | |
| SCHEMBL30133429 | 0.82 | KMT2A (0.45) | MEN1KMT2AALPLARNR1H3 | |
| SCHEMBL30133436 | 0.75 | MEN1 (0.41) | MEN1KMT2ASCN2ANR1H3 | |
| SCHEMBL23861037 | 0.75 | MEN1 (0.41) | MEN1KMT2ASCN2ANR1H3 | |
| SCHEMBL23861034 | 0.69 | MEN1 (0.37) | MEN1KMT2AALPLARHSD11B1 | |
| SCHEMBL30133451 | 0.69 | MEN1 (0.37) | MEN1KMT2AALPLARHSD11B1 | |
| SCHEMBL7802728 | 0.66 | KMT2A (0.54) | MEN1KMT2ASCN2ANR1H3 | |
| SCHEMBL9837203 | 0.66 | RXFP1 (0.38) | MEN1KMT2AALPLAR | |
| SCHEMBL893875 | 0.65 | MEN1 (0.44) | MEN1KMT2AALPLAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605466-B | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-115605466-A | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司（US） | 2023-01-13 | — | — | CN | disclosed |