Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 12/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20027682 | 1.00 | CAPN1 (0.56) | CAPN1ACECTSB | |
| SCHEMBL30133574 | 0.80 | CAPN1 (0.60) | CAPN1CTSB | |
| SCHEMBL20027691 | 0.80 | CAPN1 (0.60) | CAPN1CTSB | |
| SCHEMBL20027780 | 0.80 | CAPN1 (0.51) | CAPN1ACECTSB | |
| SCHEMBL20027878 | 0.78 | CAPN1 (0.55) | CAPN1CTSB | |
| SCHEMBL20027730 | 0.78 | CAPN1 (0.55) | CAPN1CTSB | |
| SCHEMBL7377270 | 0.77 | CAPN1 (0.67) | CAPN1ACE | |
| SCHEMBL7375338 | 0.77 | CAPN1 (0.67) | CAPN1ACE | |
| SCHEMBL22897077 | 0.77 | CAPN1 (0.57) | CAPN1CTSB | |
| SCHEMBL22897295 | 0.76 | CAPN1 (0.50) | CAPN1ACECTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220324814-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPEUTICS INC (US) | 2022-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220324814-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | CAPNS1, CAPN9, CAPN1 | CAPN1 3/4885ACE 956/4885CTSB 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.