Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 20/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20027822 | 1.00 | CAPN1 (0.50) | CAPN1CTSLCTSBCTSS | |
| SCHEMBL20027656 | 0.87 | CAPN1 (0.52) | CAPN1 | |
| SCHEMBL30133643 | 0.87 | CAPN1 (0.52) | CAPN1 | |
| SCHEMBL22897223 | 0.79 | CAPN1 (0.53) | CAPN1CTSS | |
| SCHEMBL24010407 | 0.78 | CAPN1 (0.60) | CAPN1 | |
| SCHEMBL20028399 | 0.78 | CAPN1 (0.52) | CAPN1CTSLCTSBCTSS | |
| SCHEMBL22896257 | 0.77 | CAPN1 (0.57) | CAPN1CTSLCTSBCTSS | |
| SCHEMBL20028626 | 0.77 | CAPN1 (0.52) | CAPN1CTSLCTSBCTSS | |
| SCHEMBL21854323 | 0.77 | CAPN1 (0.52) | CAPN1CTSLCTSBCTSS | |
| SCHEMBL30133658 | 0.76 | CAPN1 (0.53) | CAPN1CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220324814-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPEUTICS INC (US) | 2022-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220324814-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | CAPNS1, CAPN9, CAPN1 | CAPN1 3/4885CTSL 234/4885CTSB 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.