SCHEMBL30134232

SCHEMBL30134232

CC(O)c1ccc(F)cc1C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 5/20 0.47
DPP4 P27487 1/20 0.41
IDO1 P14902 2/20 0.40
SLC6A2 P23975 6/20 0.39
SLC6A4 P31645 6/20 0.39
SLC6A3 Q01959 2/20 0.39
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
LIPG Q9Y5X9 1/20 0.34
KCNH2 Q12809 1/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3736531 1.00 PDE2A (0.47) PDE2ADPP4IDO1SLC6A2SLC6A4
SCHEMBL30133781 0.87 PDE2A (0.42) PDE2ADPP4IDO1SLC6A2SLC6A4
SCHEMBL4547922 0.84 NOTUM (0.44) PDE2ADPP4IDO1SLC6A2SLC6A4
SCHEMBL30133925 0.81 PDE2A (0.47) PDE2ASLC6A2
SCHEMBL27793378 0.81 P2RX7 (0.47) PDE2ADPP4IDO1SLC6A2SLC6A4
SCHEMBL27499243 0.81 PDE2A (0.47) PDE2A
SCHEMBL6815689 0.81 DPP4 (0.43) PDE2ADPP4IDO1SLC6A2SLC6A4
SCHEMBL26619829 0.81 DPP4 (0.43) PDE2ADPP4IDO1SLC6A2SLC6A4
SCHEMBL19898274 0.81 PDE2A (0.66) PDE2ACES2LIPG
Hydrochloric Acid SCHEMBL14121597 0.79 IDO1 (0.45) PDE2ADPP4IDO1SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119176784-A Chlorofluoroether bacteria Synthesis process of azole 安徽久易农业股份有限公司 2024-12-24 CN claimed
EP-4658650-A1 HETEROCYCLIC COMPOUNDS Beone Medicines I GmbH (CH) 2025-12-10 EP disclosed
EP-4658655-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES Beone Medicines I GmbH (CH) 2025-12-10 EP disclosed
CN-113939295-B Pyridazinones and methods of use thereof 金翅雀生物公司 2025-05-16 CN disclosed
CN-119176784-A Chlorofluoroether bacteria Synthesis process of azole 安徽久易农业股份有限公司 2024-12-24 CN disclosed
CN-119176784-A Chlorofluoroether bacteria Synthesis process of azole 安徽久易农业股份有限公司 2024-12-24 CN disclosed
CN-119119033-A Pyrazolopyridone compounds 百济神州有限公司 2024-12-13 CN disclosed
CN-119060036-A ATF6 inhibitors and uses thereof 阿尔托斯实验室公司 2024-12-03 CN disclosed
EP-4457224-A1 HETEROCYCLIC COMPOUNDS BeiGene Switzerland GmbH (CH) 2024-11-06 EP disclosed
CN-112313224-B ATF6 inhibitors and uses thereof 阿尔托斯实验室公司 2024-08-13 CN disclosed
WO-2024160277-A1 HETEROCYCLIC COMPOUNDS BEIGENE, LTD. (KY) 2024-08-08 WO disclosed
WO-2024160278-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEIGENE, LTD. (KY) 2024-08-08 WO disclosed
CN-118451073-A Heterocyclic compounds 百济神州有限公司 2024-08-06 CN disclosed
EP-4380936-A1 PYRAZOLOPYRIDINONE COMPOUNDS BeiGene, Ltd. (KY) 2024-06-12 EP disclosed
CN-117836296-A Pyrazolopyridone compounds 百济神州有限公司 2024-04-05 CN disclosed
WO-2023125681-A1 HETEROCYCLIC COMPOUNDS BEIGENE, LTD. (KY) 2023-07-06 WO disclosed
WO-2023011456-A1 PYRAZOLOPYRIDINONE COMPOUNDS BEIGENE, LTD. (KY) 2023-02-09 WO disclosed