Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | F2RL1 | P55085 | 3/20 | 0.35 |
| ▸ | PER2 | O15055 | 2/20 | 0.34 |
| ▸ | CRY1 | Q16526 | 2/20 | 0.34 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17215607 | 1.00 | MEN1 (0.41) | MEN1KMT2APDE2ACES2CES1 | |
| SCHEMBL12248153 | 1.00 | MEN1 (0.41) | MEN1KMT2APDE2ACES2CES1 | |
| SCHEMBL13265101 | 1.00 | MEN1 (0.41) | MEN1KMT2APDE2ACES2CES1 | |
| SCHEMBL19757665 | 0.83 | PDE2A (0.49) | MEN1KMT2APDE2ACES2CES1 | |
| SCHEMBL24006637 | 0.83 | MEN1 (0.41) | MEN1KMT2APDE2ACES2CES1 | |
| SCHEMBL16629395 | 0.83 | MEN1 (0.41) | MEN1KMT2APDE2ACES2CES1 | |
| SCHEMBL12869835 | 0.83 | MEN1 (0.41) | MEN1KMT2APDE2ACES2CES1 | |
| SCHEMBL84044 | 0.82 | ALDH1A1 (0.41) | MEN1KMT2A | |
| SCHEMBL20352546 | 0.81 | PDE2A (0.35) | PDE2ACES2CES1CYP2D6GCGR | |
| SCHEMBL20336551 | 0.80 | PDE2A (0.35) | MEN1KMT2APDE2ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119033-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-12-13 | — | — | CN | disclosed |
| EP-4380936-A1 | PYRAZOLOPYRIDINONE COMPOUNDS | BeiGene, Ltd. (KY) | 2024-06-12 | — | — | EP | disclosed |
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | disclosed |
| WO-2023011456-A1 | PYRAZOLOPYRIDINONE COMPOUNDS | BEIGENE, LTD. (KY) | 2023-02-09 | — | — | WO | disclosed |