SCHEMBL30134865

SCHEMBL30134865

CC(C)C[C@@H](N)C(=O)Nc1cccc(-c2ccnc3[nH]ccc23)c1

nearest known ligand 0.78

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CIT O14578 20/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30134879 0.88 CIT (1.00) CIT
SCHEMBL30134861 0.88 CIT (1.00) CIT
SCHEMBL30135135 0.85 CIT (0.80) CIT
SCHEMBL30134848 0.85 CIT (1.00) CIT
SCHEMBL30134975 0.84 CIT (1.00) CIT
SCHEMBL30134925 0.84 CIT (1.00) CIT
SCHEMBL30134913 0.84 CIT (1.00) CIT
SCHEMBL30135098 0.84 CIT (1.00) CIT
SCHEMBL30134903 0.84 CIT (1.00) CIT
SCHEMBL30134996 0.83 CIT (1.00) CIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243196-A1 CITRON KINASE INHIBITORS THE CLEVELAND CLINIC FOUNDATION 2025-07-31 US disclosed
WO-2022216717-A1 CITRON KINASE INHIBITORS THE CLEVELAND CLINIC FOUNDATION (US) 2022-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243196-A1 CITRON KINASE INHIBITORS CHEK2, CILK1, DCK CIT 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.