Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 20/20 | 0.61 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27087178 | 1.00 | USP1 (0.61) | USP1WDR48 | |
| SCHEMBL30135371 | 0.90 | USP1 (0.63) | USP1WDR48 | |
| SCHEMBL27087071 | 0.90 | USP1 (0.63) | USP1WDR48 | |
| SCHEMBL27086985 | 0.89 | USP1 (0.60) | USP1WDR48 | |
| SCHEMBL30135370 | 0.89 | USP1 (0.60) | USP1WDR48 | |
| SCHEMBL31423557 | 0.87 | USP1 (0.61) | USP1WDR48 | |
| SCHEMBL31293589 | 0.86 | USP1 (0.60) | USP1 | |
| SCHEMBL27086993 | 0.85 | USP1 (0.57) | USP1 | |
| SCHEMBL30135372 | 0.85 | USP1 (0.57) | USP1 | |
| SCHEMBL30135298 | 0.84 | USP1 (0.58) | USP1WDR48 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4319758-A1 | INHIBITING UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) | Forma Therapeutics, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022216820-A1 | INHIBITING UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) | FORMA THERAPEUTICS, INC. (US) | 2022-10-13 | — | — | WO | disclosed |