Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6610334 | 0.82 | MAPT (0.61) | MAPTALDH1A1MAPK1LMNASIRT6 | |
| SCHEMBL4003076 | 0.82 | MAPT (0.61) | MAPTALDH1A1MAPK1LMNASIRT6 | |
| SCHEMBL4003069 | 0.82 | MAPT (0.61) | MAPTALDH1A1MAPK1LMNASIRT6 | |
| SCHEMBL9983992 | 0.82 | MAPT (0.61) | MAPTALDH1A1MAPK1LMNASIRT6 | |
| SCHEMBL16651521 | 0.82 | MAPT (0.61) | MAPTALDH1A1MAPK1LMNASIRT6 | |
| SCHEMBL2018527 | 0.82 | MAPT (0.61) | MAPTALDH1A1MAPK1LMNASIRT6 | |
| SCHEMBL521266 | 0.81 | MAPT (0.68) | MAPTALDH1A1MAPK1LMNAPOLB | |
| SCHEMBL12005041 | 0.80 | MAPT (0.67) | MAPTALDH1A1MAPK1LMNAPOLB | |
| SCHEMBL4714774 | 0.78 | MAPT (0.58) | MAPTALDH1A1MAPK1LMNASIRT6 | |
| SCHEMBL6716274 | 0.78 | MAPT (0.56) | MAPTALDH1A1MAPK1LMNASIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022216098-A1 | NOVEL LRRK2 INHIBITOR | 주식회사 스탠다임 | 2022-10-13 | — | — | WO | disclosed |