Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4003069 | 1.00 | MAPT (0.61) | MAPTALDH1A1MAPK1LMNASIRT6 | |
| SCHEMBL6873751 | 0.91 | MAPT (0.56) | MAPTALDH1A1MAPK1LMNASIRT6 | |
| SCHEMBL2126870 | 0.91 | MAPT (0.56) | MAPTALDH1A1MAPK1LMNASIRT6 | |
| SCHEMBL1750127 | 0.84 | MAPT (0.58) | MAPTALDH1A1LMNASIRT6POLB | |
| SCHEMBL31669360 | 0.83 | MAPT (0.49) | MAPTALDH1A1LMNASIRT6POLB | |
| SCHEMBL2018527 | 0.82 | MAPT (0.61) | MAPTALDH1A1MAPK1LMNASIRT6 | |
| SCHEMBL9983992 | 0.82 | MAPT (0.61) | MAPTALDH1A1MAPK1LMNASIRT6 | |
| SCHEMBL30135522 | 0.82 | MAPT (0.61) | MAPTALDH1A1MAPK1LMNASIRT6 | |
| SCHEMBL16651521 | 0.82 | MAPT (0.61) | MAPTALDH1A1MAPK1LMNASIRT6 | |
| SCHEMBL6610334 | 0.82 | MAPT (0.61) | MAPTALDH1A1MAPK1LMNASIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110291085-B | Mutant isocitrate dehydrogenase inhibitors, compositions and methods thereof | 艾科生物科技有限公司 | 2023-01-24 | — | — | CN | disclosed |
| WO-2013012827-A1 | DIAMINOCYCLOHEXANE COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-01-24 | — | — | WO | disclosed |
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |