Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 17/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30643706 | 0.86 | MAPT (0.45) | P2RY12OPRD1OPRK1 | |
| SCHEMBL25034770 | 0.85 | GPR119 (0.50) | — | |
| SCHEMBL30830960 | 0.85 | GPR119 (0.50) | — | |
| SCHEMBL30066310 | 0.84 | P2RY12 (0.41) | P2RY12SIGMAR1OPRD1OPRK1 | |
| SCHEMBL30066441 | 0.82 | P2RY12 (0.43) | P2RY12TMEM97SIGMAR1CHRM4 | |
| SCHEMBL30066289 | 0.82 | P2RY12 (0.43) | P2RY12TMEM97SIGMAR1CHRM4 | |
| SCHEMBL30066338 | 0.81 | TMEM97 (0.47) | TMEM97SIGMAR1CHRM4 | |
| SCHEMBL30441390 | 0.81 | TMEM97 (0.47) | TMEM97SIGMAR1 | |
| SCHEMBL31127679 | 0.81 | PRMT5 (0.46) | P2RY12CHRM4OPRD1OPRK1 | |
| SCHEMBL30965789 | 0.80 | HTT (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4157849-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2023-04-05 | — | — | EP | disclosed |
| WO-2023017446-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023018238-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |