Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | RECQL | P46063 | 1/20 | 0.74 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.67 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.62 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.60 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24104691 | 1.00 | KDM4E (0.74) | KDM4ERECQLEPHX2HSD17B10DYRK1A | |
| SCHEMBL350341 | 0.89 | HSD17B10 (0.76) | KDM4ERECQLEPHX2HSD17B10DYRK1A | |
| SCHEMBL4921069 | 0.87 | MEN1 (0.68) | KDM4ERECQLEPHX2HSD17B10DYRK1A | |
| SCHEMBL4918017 | 0.86 | RAB9A (0.79) | KDM4ERECQLHSD17B10DYRK1AMEN1 | |
| SCHEMBL18851598 | 0.86 | KDM4E (0.63) | KDM4ERECQLEPHX2HSD17B10DYRK1A | |
| SCHEMBL540965 | 0.86 | MAPT (0.79) | KDM4ERECQLEPHX2DYRK1ADYRK1B | |
| SCHEMBL30263006 | 0.86 | KDM4E (0.61) | KDM4ERECQLEPHX2HSD17B10DYRK1A | |
| SCHEMBL26034880 | 0.85 | CXCR2 (0.83) | KDM4ERECQLDYRK1AMEN1KMT2A | |
| SCHEMBL4919955 | 0.85 | KDM4E (1.00) | KDM4ERECQLHSD17B10MEN1KMT2A | |
| SCHEMBL24104685 | 0.85 | EPHX2 (1.00) | KDM4ERECQLEPHX2HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515944-A | Benzothiazole derivative and application thereof | 沈阳药科大学 | 2022-12-23 | — | — | CN | claimed |
| CN-113831301-B | Benzothiazole derivative and application thereof | 沈阳药科大学 | 2023-06-06 | — | — | CN | disclosed |