Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 9/20 | 0.61 |
| ▸ | KDR | P35968 | 7/20 | 0.61 |
| ▸ | TEK | Q02763 | 6/20 | 0.61 |
| ▸ | LCK | P06239 | 4/20 | 0.61 |
| ▸ | EGFR | P00533 | 6/20 | 0.58 |
| ▸ | ABL1 | P00519 | 5/20 | 0.58 |
| ▸ | ABL2 | P42684 | 5/20 | 0.58 |
| ▸ | RET | P07949 | 1/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.56 |
| ▸ | PRKDC | P78527 | 1/20 | 0.56 |
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29780906 | 0.90 | RET (0.56) | SRCKDRTEKLCKEGFR | |
| SCHEMBL29780892 | 0.78 | RET (0.53) | SRCKDRTEKLCKEGFR | |
| SCHEMBL16236508 | 0.78 | RET (0.53) | SRCKDRTEKLCKRET | |
| SCHEMBL27535239 | 0.76 | SRC (0.58) | SRCKDRTEKLCKEGFR | |
| SCHEMBL29552512 | 0.76 | TEK (1.00) | SRCKDRTEKLCKEGFR | |
| SCHEMBL7005359 | 0.76 | TEK (1.00) | SRCKDRTEKLCKEGFR | |
| SCHEMBL16202367 | 0.76 | SRC (0.67) | SRCKDRTEKLCKEGFR | |
| SCHEMBL7007567 | 0.75 | KDR (0.71) | SRCKDRTEKLCKEGFR | |
| SCHEMBL15576330 | 0.75 | SRC (0.68) | SRCKDRTEKLCKEGFR | |
| SCHEMBL2073298 | 0.75 | KDR (0.70) | SRCKDRTEKLCKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016296-A1 | HETEROCYCLIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-02-16 | — | — | WO | disclosed |