Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15059750 | 0.83 | HCRTR1 (0.44) | HCRTR1HCRTR2MAPTALDH1A1ALOX12 | |
| SCHEMBL31177639 | 0.82 | HCRTR1 (0.42) | HCRTR1HCRTR2MAPTALDH1A1ALOX12 | |
| SCHEMBL20476237 | 0.80 | ALDH1A1 (0.40) | HCRTR1HCRTR2MAPTALDH1A1ALOX12 | |
| SCHEMBL30615503 | 0.79 | MAPT (0.65) | MAPTALDH1A1ALOX12LMNANPSR1 | |
| SCHEMBL31492307 | 0.79 | HTT (0.51) | HCRTR1HCRTR2MAPTALDH1A1ALOX12 | |
| SCHEMBL21464265 | 0.79 | MAPT (0.65) | MAPTALDH1A1ALOX12LMNANPSR1 | |
| SCHEMBL1671875 | 0.79 | HCRTR1 (0.44) | HCRTR1HCRTR2MAPTALDH1A1ALOX12 | |
| SCHEMBL30136676 | 0.77 | MAPT (0.57) | MAPTALDH1A1ALOX12LMNANPSR1 | |
| SCHEMBL4966461 | 0.77 | MAPT (0.62) | MAPTALDH1A1ALOX12LMNANPSR1 | |
| SCHEMBL30933194 | 0.76 | MAPT (0.41) | HCRTR1HCRTR2MAPTALDH1A1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024199430-A1 | PI3Kα INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | 长春金赛药业有限责任公司 | 2024-10-03 | — | — | WO | disclosed |
| CN-117813293-A | Urea derivatives useful for the treatment of cancer | 蝎子疗法股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| EP-4334298-A1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | Scorpion Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022265993-A1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |