Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 3/20 | 0.37 |
| ▸ | GABRD | O14764 | 3/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20559261 | 1.00 | RAB9A (0.42) | RAB9ANPC1MAPTCYP1A2CYP3A4 | |
| SCHEMBL24756010 | 1.00 | RAB9A (0.42) | RAB9ANPC1MAPTCYP1A2CYP3A4 | |
| SCHEMBL20559260 | 1.00 | RAB9A (0.42) | RAB9ANPC1MAPTCYP1A2CYP3A4 | |
| SCHEMBL30933170 | 0.87 | RAB9A (0.38) | RAB9ANPC1MAPTCYP1A2CYP3A4 | |
| SCHEMBL24755661 | 0.87 | RAB9A (0.38) | RAB9ANPC1MAPTCYP1A2CYP3A4 | |
| SCHEMBL24755663 | 0.87 | RAB9A (0.38) | RAB9ANPC1MAPTCYP1A2CYP3A4 | |
| SCHEMBL24755986 | 0.87 | RAB9A (0.38) | RAB9ANPC1MAPTCYP1A2CYP3A4 | |
| SCHEMBL30136617 | 0.87 | RAB9A (0.38) | RAB9ANPC1MAPTCYP1A2CYP3A4 | |
| SCHEMBL12248495 | 0.86 | RAB9A (0.41) | RAB9ANPC1MAPTCYP1A2CYP3A4 | |
| SCHEMBL24756449 | 0.83 | RAB9A (0.39) | RAB9ANPC1MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813293-A | Urea derivatives useful for the treatment of cancer | 蝎子疗法股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| EP-4334298-A1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | Scorpion Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022265993-A1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |