SCHEMBL30136739

SCHEMBL30136739

N#Cc1ccc(NC(=O)Oc2ccccc2)cn1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
MAPT P10636 3/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
KDM4E B2RXH2 2/20 0.52
THRB P10828 1/20 0.52
GFER P55789 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
RAD51 Q06609 1/20 0.51
GAA P10253 2/20 0.51
LMNA P02545 1/20 0.51
TP53 P04637 1/20 0.51
FAAH O00519 7/20 0.49
HTT P42858 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
KCNQ3 O43525 2/20 0.48
KCNQ2 O43526 2/20 0.48
AR P10275 1/20 0.48
CHEK1 O14757 1/20 0.47
PORCN Q9H237 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL896642 1.00 ALDH1A1 (0.52) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL27794530 0.87 ALDH1A1 (0.54) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL27785451 0.86 CHEK1 (0.45) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL590790 0.83 MAPT (0.47) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL24757755 0.83 ALDH1A1 (0.51) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL31129270 0.81 AR (0.57) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL31125084 0.81 CHEK1 (0.59) ALDH1A1MAPTCHEK1
SCHEMBL2589885 0.81 CHEK1 (0.59) ALDH1A1MAPTCHEK1
SCHEMBL896314 0.80 KCNQ3 (0.64) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL27857353 0.80 KCNQ3 (0.52) MAPTMEN1KMT2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4334298-B1 UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER SCORPION THERAPEUTICS INC (US) 2026-02-18 EP disclosed
US-20250250259-A1 METHODS FOR TREATING CANCER SCORPION THERAPEUTICS, INC. 2025-08-07 US disclosed
US-12312341-B2 Methods for treating cancer SCORPION THERAPEUTICS, INC. (US) 2025-05-27 US disclosed
US-20240400543-A1 METHODS FOR TREATING CANCER SCORPION THERAPEUTICS, INC. 2024-12-05 US disclosed
US-20240300939-A1 UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER SCORPION THERAPEUTICS, INC. 2024-09-12 US disclosed
US-12084434-B2 Methods for treating cancer SCORPION THERAPEUTICS, INC. (US) 2024-09-10 US disclosed
EP-4334298-A1 UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER Scorpion Therapeutics, Inc. (US) 2024-03-13 EP disclosed
US-20240076289-A1 METHODS FOR TREATING CANCER SCORPION THERAPEUTICS, INC. 2024-03-07 US disclosed
US-11897871-B1 Methods for treating cancer SCORPION THERAPEUTICS, INC. (US) 2024-02-13 US disclosed
WO-2022265993-A1 UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER SCORPION THERAPEUTICS, INC. (US) 2022-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240300939-A1 UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER PIK3CA, PIK3CG, PIK3CD ALDH1A1 1105/4885MAPT 1252/4885MEN1 2890/4885
US-11897871-B1 Methods for treating cancer PIK3CA, PTEN, BRCA1 ALDH1A1 1084/4885MAPT 2262/4885MEN1 2531/4885
US-12312341-B2 Methods for treating cancer PIK3CA, PTEN, BRCA1 ALDH1A1 1084/4885MAPT 2262/4885MEN1 2531/4885
US-20240076289-A1 METHODS FOR TREATING CANCER PIK3CA, PTEN, BRCA1 ALDH1A1 1084/4885MAPT 2262/4885MEN1 2531/4885
US-20250250259-A1 METHODS FOR TREATING CANCER PIK3CA, PTEN, BRCA1 ALDH1A1 1084/4885MAPT 2262/4885MEN1 2531/4885
US-20240400543-A1 METHODS FOR TREATING CANCER PIK3CA, PTEN, BRCA1 ALDH1A1 1084/4885MAPT 2262/4885MEN1 2531/4885
US-12084434-B2 Methods for treating cancer PIK3CA, PTEN, BRCA1 ALDH1A1 1084/4885MAPT 2262/4885MEN1 2531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.