SCHEMBL30137211

SCHEMBL30137211

CNS(=O)(=O)CCc1ccc2c(ccn2C(=O)OC(C)(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OXER1 Q8TDS5 1/20 0.40
PIK3CD O00329 2/20 0.39
ABL1 P00519 2/20 0.39
EGFR P00533 2/20 0.39
HCK P08631 2/20 0.39
SRC P12931 2/20 0.39
KDR P35968 2/20 0.39
PIK3CA P42336 2/20 0.39
PIK3CB P42338 2/20 0.39
MTOR P42345 2/20 0.39
PIK3CG P48736 2/20 0.39
EPHB4 P54760 2/20 0.39
PRKDC P78527 2/20 0.39
PI4KB Q9UBF8 2/20 0.39
NR1H2 P55055 12/20 0.39
S1PR1 P21453 1/20 0.39
NR1H3 Q13133 3/20 0.36
ACLY P53396 1/20 0.36
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28967316 1.00 OXER1 (0.40) OXER1PIK3CDABL1EGFRHCK
SCHEMBL30137213 0.84 HTR6 (0.40) OXER1PIK3CDABL1EGFRHCK
SCHEMBL10820368 0.82 OXER1 (0.48) OXER1PIK3CDABL1EGFRHCK
SCHEMBL1056456 0.82 NR1H2 (0.46) OXER1PIK3CDABL1EGFRHCK
SCHEMBL31370744 0.81 NR1H2 (0.45) OXER1PIK3CDABL1EGFRHCK
SCHEMBL13456554 0.81 KDR (0.42) OXER1PIK3CDABL1EGFRHCK
SCHEMBL28485964 0.80 NR1H2 (0.55) OXER1PIK3CDABL1EGFRHCK
SCHEMBL6099616 0.80 NR1H2 (0.49) OXER1PIK3CDABL1EGFRHCK
SCHEMBL29658586 0.80 PIK3CD (0.44) OXER1PIK3CDABL1EGFRHCK
SCHEMBL1057433 0.80 PIK3CD (0.44) OXER1PIK3CDABL1EGFRHCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115611854-B New method for preparing naratriptan and derivatives thereof 天津师范大学 2024-03-26 CN disclosed
CN-115611781-B New method for preparing alkyl sulfonamide from fatty amine sulfonyl chloride 天津师范大学 2024-03-26 CN disclosed
CN-115611781-A Novel method for preparing alkyl sulfonamide from fatty amine sulfonyl chloride 天津师范大学 2023-01-17 CN disclosed
CN-115611854-A New method for preparing naratriptan and derivatives thereof 天津师范大学 2023-01-17 CN disclosed