Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1655443 | 1.00 | RAB9A (0.45) | RAB9ALRRK2LMNAHTTCYP11B1 | |
| SCHEMBL2259993 | 0.91 | LRRK2 (0.37) | RAB9ALRRK2LMNAHTTMAPT | |
| SCHEMBL83685 | 0.89 | MAPT (0.46) | LMNAMAPTALDH1A1POLBKDM4E | |
| SCHEMBL19328940 | 0.89 | CSNK2A2 (0.37) | RAB9ALRRK2ALDH1A1KDM4EMEN1 | |
| SCHEMBL1301071 | 0.88 | MAPT (0.38) | MAPTALDH1A1POLBKDM4EGAA | |
| SCHEMBL6730444 | 0.88 | MAPT (0.39) | MAPTALDH1A1POLBKDM4EGAA | |
| SCHEMBL1497638 | 0.88 | MAPT (0.39) | MAPTALDH1A1POLBKDM4EGAA | |
| SCHEMBL1658265 | 0.87 | MAPT (0.38) | MAPTALDH1A1POLBKDM4EGAA | |
| SCHEMBL12064247 | 0.87 | MAPT (0.38) | MAPTALDH1A1POLBKDM4EGAA | |
| SCHEMBL3677899 | 0.87 | GAA (0.41) | LMNAMAPTALDH1A1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101631464-B | 2,3-dihydroimidazo [1,2-c ] quinazoline substituted derivatives for the treatment of hyperproliferative diseases and angiogenesis-related diseases | 拜耳知识产权有限责任公司 | 2022-12-06 | — | — | CN | disclosed |