Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30140315 | 0.94 | EGFR (0.63) | EGFRERBB2KCNH2 | |
| SCHEMBL30140404 | 0.94 | EGFR (0.63) | EGFRERBB2KCNH2 | |
| SCHEMBL30140359 | 0.94 | EGFR (0.63) | EGFRERBB2KCNH2 | |
| SCHEMBL30140190 | 0.92 | EGFR (0.53) | EGFRERBB2 | |
| SCHEMBL23570485 | 0.92 | EGFR (0.57) | EGFRERBB2KCNH2 | |
| SCHEMBL30140397 | 0.90 | EGFR (0.59) | EGFRERBB2KCNH2 | |
| SCHEMBL30140101 | 0.90 | EGFR (0.58) | EGFRERBB2KCNH2 | |
| SCHEMBL30140337 | 0.90 | EGFR (0.55) | EGFRERBB2KCNH2 | |
| SCHEMBL30140347 | 0.90 | EGFR (0.55) | EGFRERBB2KCNH2 | |
| SCHEMBL30140270 | 0.89 | EGFR (0.59) | EGFRERBB2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266426-A1 | 6-(HETEROCYCLOALKYL-OXY)-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |