Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30140337 | 1.00 | EGFR (0.55) | EGFRERBB2KCNH2KDR | |
| SCHEMBL30140300 | 0.94 | EGFR (0.58) | EGFRERBB2KCNH2 | |
| SCHEMBL23570485 | 0.91 | EGFR (0.57) | EGFRERBB2KCNH2KDR | |
| SCHEMBL23570484 | 0.91 | EGFR (0.53) | EGFRERBB2KCNH2KDR | |
| SCHEMBL30140117 | 0.90 | EGFR (0.58) | EGFRERBB2KCNH2 | |
| SCHEMBL30140293 | 0.89 | EGFR (0.55) | EGFRERBB2KCNH2KDR | |
| SCHEMBL30140160 | 0.89 | GPR119 (0.45) | EGFRERBB2 | |
| SCHEMBL30140315 | 0.88 | EGFR (0.63) | EGFRERBB2KCNH2 | |
| SCHEMBL30140404 | 0.88 | EGFR (0.63) | EGFRERBB2KCNH2 | |
| SCHEMBL30140359 | 0.88 | EGFR (0.63) | EGFRERBB2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266426-A1 | 6-(HETEROCYCLOALKYL-OXY)-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |