Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21747131 | 1.00 | KLKB1 (0.36) | KLKB1NR1H2 | |
| SCHEMBL21747035 | 0.84 | KLKB1 (0.36) | KLKB1 | |
| SCHEMBL30140677 | 0.84 | KLKB1 (0.36) | KLKB1 | |
| SCHEMBL21712938 | 0.80 | NR1H2 (0.45) | KLKB1NR1H2 | |
| SCHEMBL21736645 | 0.80 | NR1H2 (0.45) | KLKB1NR1H2 | |
| SCHEMBL26307833 | 0.76 | KLKB1 (0.30) | KLKB1 | |
| SCHEMBL21736662 | 0.70 | KLKB1 (0.47) | KLKB1 | |
| SCHEMBL21712913 | 0.68 | KLKB1 (0.47) | KLKB1 | |
| SCHEMBL21736635 | 0.68 | KLKB1 (0.45) | KLKB1 | |
| SCHEMBL23469646 | 0.68 | KLKB1 (0.47) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039181-B | Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein | 勃林格殷格翰国际有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-110546146-B | Heteroaryl carboxamide derivatives as plasma kallikrein inhibitors | 勃林格殷格翰国际有限公司 | 2023-02-21 | — | — | CN | disclosed |