Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22166243 | 0.89 | KLKB1 (0.59) | KLKB1BTK | |
| Lithium Ion SCHEMBL31033178 | 0.87 | KLKB1 (0.48) | KLKB1BTK | |
| SCHEMBL23469584 | 0.87 | KLKB1 (0.59) | KLKB1BTK | |
| SCHEMBL23469581 | 0.86 | KLKB1 (0.56) | KLKB1BTK | |
| Lithium Ion SCHEMBL30140698 | 0.82 | KLKB1 (0.58) | KLKB1BTK | |
| SCHEMBL23830240 | 0.80 | KLKB1 (0.55) | KLKB1BTK | |
| SCHEMBL21736872 | 0.77 | KLKB1 (0.47) | KLKB1BTK | |
| SCHEMBL21712913 | 0.76 | KLKB1 (0.47) | KLKB1BTK | |
| SCHEMBL30140619 | 0.76 | KLKB1 (1.00) | KLKB1BTK | |
| SCHEMBL23769633 | 0.76 | KLKB1 (0.46) | KLKB1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110546146-B | Heteroaryl carboxamide derivatives as plasma kallikrein inhibitors | 勃林格殷格翰国际有限公司 | 2023-02-21 | — | — | CN | disclosed |