Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21712913 | 0.90 | KLKB1 (0.47) | KLKB1BTK | |
| Lithium Ion SCHEMBL30140720 | 0.87 | KLKB1 (0.60) | KLKB1BTK | |
| SCHEMBL21713031 | 0.87 | KLKB1 (0.45) | KLKB1BTK | |
| SCHEMBL31033242 | 0.87 | KLKB1 (0.45) | KLKB1BTK | |
| Lithium Ion SCHEMBL30140676 | 0.84 | KLKB1 (0.63) | KLKB1 | |
| Lithium Ion SCHEMBL30140715 | 0.83 | KLKB1 (0.46) | KLKB1BTK | |
| SCHEMBL23769736 | 0.79 | KLKB1 (0.58) | KLKB1BTK | |
| SCHEMBL29906589 | 0.79 | KLKB1 (0.58) | KLKB1BTK | |
| SCHEMBL21736635 | 0.78 | KLKB1 (0.45) | KLKB1 | |
| SCHEMBL20540796 | 0.77 | KLKB1 (0.47) | KLKB1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3837252-B1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2025-12-10 | — | — | EP | disclosed |
| CN-113039181-B | Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein | 勃林格殷格翰国际有限公司 | 2024-08-13 | — | — | CN | disclosed |