SCHEMBL30140824

SCHEMBL30140824

O=C(CO)CC[C@H]1CCNC1=O

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 3/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
FOLH1 Q04609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30140717 0.90 L3MBTL1 (0.39) CCR2L3MBTL1FOLH1
SCHEMBL25313700 0.81 FOLH1 (0.46) CCR2L3MBTL1FOLH1
SCHEMBL25313694 0.81 FOLH1 (0.46) CCR2L3MBTL1FOLH1
SCHEMBL24486583 0.80 GAA (0.35) CCR2L3MBTL1FOLH1
SCHEMBL30170353 0.80 GAA (0.35) CCR2L3MBTL1FOLH1
SCHEMBL2997778 0.79
SCHEMBL30174805 0.79 KDM4E (0.36) CCR2L3MBTL1FOLH1
SCHEMBL30222769 0.79 KDM4E (0.36) CCR2L3MBTL1FOLH1
Hydrochloric Acid SCHEMBL30192546 0.79 GAA (0.34) CCR2L3MBTL1FOLH1
SCHEMBL8370882 0.78 KDM4E (0.34) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4165037-A1 ANTI-VIRAL COMPOUNDS FOR TREATING CORONAVIRUS, PICORNAVIRUS, AND NOROVIRUS INFECTIONS Aligos Therapeutics, Inc. (US) 2023-04-19 EP disclosed
WO-2022266363-A1 PROTEASE INHIBITORS FOR THE TREATMENT OF CORONAVIRUS INFECTIONS THE SCRIPPS RESEARCH INSTITUTE (US) 2022-12-22 WO disclosed