SCHEMBL301409

SCHEMBL301409

FC=CCc1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 4/20 0.48
CYP1A2 P05177 3/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2D6 P10635 3/20 0.46
TDP1 Q9NUW8 1/20 0.44
HPGD P15428 3/20 0.43
HTT P42858 2/20 0.43
ACP3 P15309 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NR1I2 O75469 1/20 0.41
DRD2 P14416 1/20 0.41
ADRA2C P18825 1/20 0.41
CNR1 P21554 1/20 0.41
SLC6A2 P23975 1/20 0.41
HTR2A P28223 1/20 0.41
SLC6A4 P31645 1/20 0.41
ADRA1A P35348 1/20 0.41
OPRK1 P41145 1/20 0.41
SLC6A3 Q01959 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8378939 0.83 CYP2C19 (0.52) CYP2C19CYP1A2CYP2C9CYP2D6TDP1
SCHEMBL1325661 0.80 TDP1 (0.48) CYP2C19CYP1A2CYP2C9CYP2D6TDP1
SCHEMBL7924285 0.80 CYP2C19 (0.48) CYP2C19CYP1A2CYP2C9CYP2D6TDP1
SCHEMBL2136855 0.80 CYP2C19 (0.50) CYP2C19CYP1A2CYP2C9CYP2D6TDP1
SCHEMBL1611481 0.80 CYP2C19 (0.50) CYP2C19CYP1A2CYP2C9CYP2D6TDP1
SCHEMBL4229398 0.80 CYP2C19 (0.48) CYP2C19CYP1A2CYP2C9CYP2D6TDP1
SCHEMBL10499434 0.80 CYP1A2 (0.48) CYP2C19CYP1A2CYP2C9CYP2D6TDP1
SCHEMBL6694933 0.80 CYP1A2 (0.48) CYP2C19CYP1A2CYP2C9CYP2D6TDP1
SCHEMBL5830944 0.79 CYP2C19 (0.56) CYP2C19CYP1A2CYP2C9CYP2D6TDP1
SCHEMBL10750285 0.78 MAOB (0.58) CYP2C19CYP1A2CYP2C9CYP2D6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1627213-B1 ANTIFRICTION BEARING PROVIDED WITH POLYMER ELECTRONICS SCHAEFFLER TECHNOLOGIES AG (DE) 2012-03-14 EP claimed
US-7827871-B2 Antifriction bearing provided with polymer electronics SCHAEFFLER KG (DE) 2010-11-09 US claimed
US-7742281-B2 Solid electrolytic capacitor SANYO ELECTRIC CO., LTD. (JP) 2010-06-22 US claimed
US-20070277612-A1 Antifriction Bearing Provided With Polymer Electronics Schaeffler Technologies AG & Co. KG (DE) 2007-12-06 US claimed
US-7827871-B2 Antifriction bearing provided with polymer electronics SCHAEFFLER KG (DE) 2010-11-09 US disclosed
US-7742281-B2 Solid electrolytic capacitor SANYO ELECTRIC CO., LTD. (JP) 2010-06-22 US disclosed
US-20080158783-A1 SOLID ELECTROLYTIC CAPACITOR SANYO ELECTRIC CO., LTD. (JP) 2008-07-03 US disclosed
US-20070277612-A1 Antifriction Bearing Provided With Polymer Electronics Schaeffler Technologies AG & Co. KG (DE) 2007-12-06 US disclosed