Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24095092 | 0.87 | KMT2A (0.61) | OPRK1KMT2AKDM1AOPRD1 | |
| SCHEMBL20556708 | 0.84 | ERN1 (0.56) | KDM1AGPR183 | |
| SCHEMBL15536173 | 0.80 | KDM1A (0.50) | OPRK1KMT2AKDM1AOPRD1 | |
| SCHEMBL30027230 | 0.80 | KDM1A (0.50) | OPRK1KMT2AKDM1AOPRD1 | |
| SCHEMBL31748198 | 0.78 | HSD11B1 (0.53) | KMT2AHSD11B1KDM1AGPR183PARP1 | |
| SCHEMBL1221599 | 0.78 | KDM1A (0.48) | OPRK1KMT2AKDM1AOPRD1HDAC1 | |
| SCHEMBL2445002 | 0.78 | SMN1; SMN2 (0.60) | KMT2A | |
| SCHEMBL3658891 | 0.77 | SMN1; SMN2 (0.46) | OPRK1KMT2AKDM1AHDAC1HDAC2 | |
| SCHEMBL1220804 | 0.77 | KDM1A (0.48) | OPRK1KMT2AKDM1AOPRD1 | |
| Hydrochloric Acid SCHEMBL30140952 | 0.77 | KMT2A (0.56) | OPRK1KMT2AENPP2ATXN2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115873069-A | Peptide amide compound, pharmaceutically acceptable salt and stereoisomer thereof, and application thereof | 天地恒一制药股份有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115707712-A | Peptide amide compound, pharmaceutically acceptable salt and stereoisomer thereof, and application thereof | 天地恒一制药股份有限公司 | 2023-02-21 | — | — | CN | disclosed |