Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24983669 | 1.00 | LMNA (0.56) | LMNAHPGDFFAR4NPC1BRD4 | |
| SCHEMBL24983419 | 0.90 | LMNA (0.51) | LMNAHPGDFFAR4NPC1BRD4 | |
| SCHEMBL30141092 | 0.90 | LMNA (0.51) | LMNAHPGDFFAR4NPC1BRD4 | |
| SCHEMBL13662895 | 0.86 | LMNA (0.58) | LMNAHPGDFFAR4BRD4USP2 | |
| SCHEMBL30141095 | 0.86 | FOLH1 (0.52) | NPC1ALDH1A1CTSVCTSLL3MBTL1 | |
| SCHEMBL6761323 | 0.86 | FOLH1 (0.52) | NPC1ALDH1A1CTSVCTSLL3MBTL1 | |
| SCHEMBL30892443 | 0.86 | LMNA (0.46) | LMNAHPGDALDH1A1TSHRL3MBTL1 | |
| SCHEMBL24983853 | 0.86 | LMNA (0.46) | LMNAHPGDALDH1A1TSHRL3MBTL1 | |
| SCHEMBL24983872 | 0.85 | MEN1 (0.48) | LMNAHPGDNPC1ALDH1A1TSHR | |
| SCHEMBL4307561 | 0.84 | LMNA (0.56) | LMNAHPGDBRD4USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794526-A | Compositions and methods for antioxidants and anti-inflammatory therapeutics | 阿万蒂生物科学股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| WO-2023288020-A1 | COMPOSITIONS AND METHODS FOR ANTIOXIDANT AND ANTI-INFLAMMATORY THERAPEUTICS | AVANTI BIOSCIENCES INC. (US) | 2023-01-19 | — | — | WO | disclosed |