SCHEMBL30141352 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	GPR119	Q8TDV5	1/20	0.51

▸	KDM4E	B2RXH2	7/20	0.46

▸	ALDH1A1	P00352	1/20	0.39

▸	GAA	P10253	1/20	0.39

▸	HRH3	Q9Y5N1	3/20	0.39

▸	CKS1B	P61024	1/20	0.39

▸	SKP1	P63208	1/20	0.39

▸	SKP2	Q13309	1/20	0.39

▸	RXFP1	Q9HBX9	1/20	0.39

▸	TSHR	P16473	1/20	0.39

▸	TP53	P04637	1/20	0.39

▸	LMNA	P02545	1/20	0.38

▸	L3MBTL1	Q9Y468	1/20	0.38

▸	THRB	P10828	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30141155	0.90	GPR119 (0.41)	GPR119KDM4EALDH1A1GAACKS1B
SCHEMBL24878910	0.83	CKS1B (0.41)	GPR119CKS1BSKP1SKP2
SCHEMBL30111113	0.83	CKS1B (0.41)	GPR119CKS1BSKP1SKP2
SCHEMBL6700495	0.83	GPR119 (0.54)	GPR119KDM4EALDH1A1GAAHRH3
SCHEMBL30896909	0.83	CKS1B (0.40)	CKS1BSKP1SKP2
SCHEMBL31605686	0.83	CKS1B (0.40)	GPR119CKS1BSKP1SKP2
SCHEMBL30896965	0.79	HCRTR2 (0.35)	CKS1BSKP1SKP2L3MBTL1
SCHEMBL6697501	0.79	CKS1B (0.61)	GPR119KDM4EALDH1A1GAACKS1B
SCHEMBL30671539	0.77	CKS1B (0.42)	CKS1BSKP1SKP2TSHR
SCHEMBL29118287	0.77	CKS1B (0.42)	CKS1BSKP1SKP2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023018155-A1	COMPOUND HAVING SHP2 PROTEIN DEGRADING ACTIVITY, AND MEDICAL USES THEREOF	주식회사 유빅스테라퓨틱스	2023-02-16	—	—	WO	disclosed