Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 13/20 | 0.42 |
| ▸ | RAF1 | P04049 | 5/20 | 0.36 |
| ▸ | BRAF | P15056 | 5/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24906222 | 1.00 | SCN10A (0.42) | SCN10ARAF1BRAFNR3C1AKR1C3 | |
| SCHEMBL24906422 | 0.89 | SCN10A (0.44) | SCN10ARAF1BRAFAKR1C3AKR1C2 | |
| SCHEMBL30141382 | 0.86 | SCN10A (0.40) | SCN10ARAF1BRAFNR3C1 | |
| SCHEMBL24906218 | 0.86 | SCN10A (0.40) | SCN10ARAF1BRAFNR3C1 | |
| SCHEMBL24758389 | 0.84 | SCN10A (0.38) | SCN10ARAF1BRAFNR3C1 | |
| SCHEMBL30141366 | 0.79 | SCN10A (0.45) | SCN10A | |
| SCHEMBL24906328 | 0.79 | SCN10A (0.45) | SCN10A | |
| SCHEMBL24906504 | 0.78 | SCN10A (0.45) | SCN10A | |
| SCHEMBL24906303 | 0.77 | SCN10A (0.43) | SCN10A | |
| SCHEMBL24906475 | 0.76 | SCN10A (0.43) | SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4355733-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2024-04-24 | — | — | EP | claimed |
| WO-2022263498-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2022-12-22 | — | — | WO | claimed |
| EP-4355733-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2024-04-24 | — | — | EP | disclosed |
| WO-2022263498-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2022-12-22 | — | — | WO | disclosed |