Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.74 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14027201 | 1.00 | MAPT (0.74) | MAPTNPSR1KCNA3KMT2AMEN1 | |
| SCHEMBL27645866 | 1.00 | MAPT (0.74) | MAPTNPSR1KCNA3KMT2AMEN1 | |
| SCHEMBL15732330 | 0.91 | MAPT (0.80) | MAPTNPSR1KCNA3KMT2AMEN1 | |
| SCHEMBL15732329 | 0.91 | MAPT (0.80) | MAPTNPSR1KCNA3KMT2AMEN1 | |
| SCHEMBL29738300 | 0.90 | MAPT (0.68) | MAPTNPSR1KCNA3KMT2AMEN1 | |
| SCHEMBL8252412 | 0.89 | CYP19A1 (0.68) | MAPTNPSR1KCNA3KMT2AMEN1 | |
| SCHEMBL662967 | 0.87 | MAPT (0.74) | MAPTNPSR1KCNA3KMT2AMEN1 | |
| SCHEMBL662966 | 0.87 | MAPT (0.74) | MAPTNPSR1KCNA3KMT2AMEN1 | |
| SCHEMBL8248887 | 0.85 | MAPT (0.70) | MAPTNPSR1KCNA3KMT2AMEN1 | |
| SCHEMBL29435861 | 0.83 | MAPT (0.80) | MAPTNPSR1KCNA3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019528-A | Compositions and methods for preventing and/or treating diseases associated with IL-23 expression | ALLSPIM公司 | 2024-05-10 | — | — | CN | claimed |
| CN-118019528-A | Compositions and methods for preventing and/or treating diseases associated with IL-23 expression | ALLSPIM公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-118019528-A | Compositions and methods for preventing and/or treating diseases associated with IL-23 expression | ALLSPIM公司 | 2024-05-10 | — | — | CN | disclosed |