Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.57 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL662966 | 1.00 | MAPT (0.74) | MAPTNPSR1KMT2AMEN1KCNA3 | |
| SCHEMBL29435861 | 0.91 | MAPT (0.80) | MAPTNPSR1KMT2AMEN1KCNA3 | |
| SCHEMBL29396796 | 0.90 | MAPT (0.68) | MAPTNPSR1KMT2AMEN1KCNA3 | |
| SCHEMBL27575849 | 0.89 | MAPT (0.58) | MAPTNPSR1KMT2AMEN1KCNA3 | |
| SCHEMBL27575851 | 0.89 | MAPT (0.58) | MAPTNPSR1KMT2AMEN1KCNA3 | |
| SCHEMBL27645866 | 0.87 | MAPT (0.74) | MAPTNPSR1KMT2AMEN1KCNA3 | |
| SCHEMBL14027201 | 0.87 | MAPT (0.74) | MAPTNPSR1KMT2AMEN1KCNA3 | |
| SCHEMBL30141565 | 0.87 | MAPT (0.74) | MAPTNPSR1KMT2AMEN1KCNA3 | |
| SCHEMBL15575116 | 0.85 | SLC5A1 (0.65) | MAPTNPSR1KMT2AMEN1KCNA3 | |
| SCHEMBL15575117 | 0.85 | SLC5A1 (0.65) | MAPTNPSR1KMT2AMEN1KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046353-A1 | CLEISTOCALYX OPERCULATUS-DERIVED COMPOUNDS HAVING INHIBITORY ACTIVITIES AGAINST AVIAN AND SWINE INFLUENZA VIRUSES OR NOVEL INFLUENZA VIRUS | CHOONG ANG VACCINE LAB. (KR) | 2012-02-23 | — | — | US | claimed |
| WO-2012023660-A1 | ANTIVIRAL DRUG FOR AVIAN AND SWINE INFLUENZA AND NOVEL FLU, OBTAINED FROM CLEISTOCALYX OPERCULATUS | 주식회사 중앙백신연구소 (KR) | 2012-02-23 | — | — | WO | claimed |
| US-20120046353-A1 | CLEISTOCALYX OPERCULATUS-DERIVED COMPOUNDS HAVING INHIBITORY ACTIVITIES AGAINST AVIAN AND SWINE INFLUENZA VIRUSES OR NOVEL INFLUENZA VIRUS | CHOONG ANG VACCINE LAB. (KR) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046353-A1 | CLEISTOCALYX OPERCULATUS-DERIVED COMPOUNDS HAVING INHIBITORY ACTIVITIES AGAINST AVIAN AND SWINE INFLUENZA VIRUSES OR NOVEL INFLUENZA VIRUS | PIGS, CLEC4M, ENGASE | MAPT 2192/4885NPSR1 3120/4885KMT2A 2848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.