SCHEMBL30142472

SCHEMBL30142472

CN(C)C(CNC(=O)N1Cc2ccc(F)cc2C1)c1ccsc1

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACKR3 P25106 1/20 0.56
NAMPT P43490 17/20 0.48
DPP8 Q6V1X1 2/20 0.43
DPP9 Q86TI2 2/20 0.43
DPP4 P27487 1/20 0.41
DPP7 Q9UHL4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19926251 1.00 ACKR3 (0.56) ACKR3NAMPTDPP8DPP9DPP4
SCHEMBL21116504 1.00 ACKR3 (0.56) ACKR3NAMPTDPP8DPP9DPP4
SCHEMBL21116506 1.00 ACKR3 (0.56) ACKR3NAMPTDPP8DPP9DPP4
Hydrochloric Acid SCHEMBL19926194 0.99 ACKR3 (0.55) ACKR3NAMPTDPP8DPP9
SCHEMBL19925894 0.91 ACKR3 (0.46) ACKR3NAMPTDPP8DPP9
SCHEMBL29974582 0.91 ACKR3 (0.53) ACKR3NAMPT
SCHEMBL19926160 0.91 ACKR3 (0.53) ACKR3NAMPT
SCHEMBL19926202 0.90 NAMPT (0.48) ACKR3NAMPTDPP8DPP9
SCHEMBL30142463 0.90 NAMPT (0.48) ACKR3NAMPTDPP8DPP9
SCHEMBL19926258 0.90 NAMPT (0.48) ACKR3NAMPTDPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843379-B Substituted ureas and methods of making and using the same 梅比斯发现公司 2022-12-30 CN disclosed