Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24073679 | 1.00 | KMT2A (0.64) | KMT2AMEN1SMN1; SMN2RXFP1NPC1 | |
| SCHEMBL11783963 | 0.87 | MEN1 (0.68) | KMT2AMEN1SMN1; SMN2RXFP1NPC1 | |
| SCHEMBL27134473 | 0.87 | KMT2A (0.77) | KMT2AMEN1SMN1; SMN2RXFP1NPC1 | |
| SCHEMBL25063018 | 0.86 | KMT2A (0.66) | KMT2AMEN1SMN1; SMN2RXFP1NPC1 | |
| SCHEMBL6815864 | 0.84 | MEN1 (0.64) | KMT2AMEN1SMN1; SMN2RXFP1NPC1 | |
| SCHEMBL24073684 | 0.84 | SMN1; SMN2 (0.74) | KMT2AMEN1SMN1; SMN2RXFP1NPC1 | |
| SCHEMBL24073672 | 0.84 | MEN1 (0.64) | KMT2AMEN1SMN1; SMN2RXFP1NPC1 | |
| SCHEMBL30142707 | 0.84 | SMN1; SMN2 (0.74) | KMT2AMEN1SMN1; SMN2RXFP1NPC1 | |
| SCHEMBL30142676 | 0.84 | MEN1 (0.64) | KMT2AMEN1SMN1; SMN2RXFP1NPC1 | |
| SCHEMBL10801453 | 0.81 | KMT2A (0.60) | KMT2AMEN1SMN1; SMN2RXFP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-02-29 | — | — | US | disclosed |
| CN-116472292-A | Modified proteins and protein degrading agents | 上海睿跃生物科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| EP-4157888-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | Cullgen (Shanghai), Inc. (CN) | 2023-04-05 | — | — | EP | disclosed |
| US-20230057177-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, MDM2 | KMT2A 1342/4885MEN1 3254/4885SMN1; SMN2 2621/4885 |
| US-20230057177-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, MDM2 | KMT2A 1342/4885MEN1 3254/4885SMN1; SMN2 2621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.