Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28337228 | 0.88 | MAPT (0.33) | TSHRENPP1HTR2CMAPT | |
| SCHEMBL28339340 | 0.87 | AURKA (0.35) | TSHRENPP1MAPTKDM4EHPGD | |
| SCHEMBL28339341 | 0.87 | AURKA (0.35) | TSHRENPP1MAPTKDM4EHPGD | |
| SCHEMBL16773148 | 0.85 | AURKA (0.30) | — | |
| SCHEMBL15389848 | 0.85 | ENPP1 (0.38) | CLK4USP2TSHRHSD17B10CYP2D6 | |
| SCHEMBL15390257 | 0.83 | AURKA (0.41) | CLK4USP2TSHRHSD17B10CYP2D6 | |
| SCHEMBL21485106 | 0.78 | LIMK2 (0.35) | — | |
| SCHEMBL21485105 | 0.78 | LIMK2 (0.35) | — | |
| SCHEMBL16755390 | 0.69 | KIT (0.47) | KDM4ETLR7 | |
| SCHEMBL16773364 | 0.69 | AURKA (0.41) | USP2TSHRHSD17B10CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590606-B | Process for preparing pyrimidylcyclopentane compounds | 豪夫迈·罗氏有限公司 | 2023-02-17 | — | — | CN | disclosed |