SCHEMBL30142944

SCHEMBL30142944

Cc1ccccc1C(C)C.[Ru+2]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.54
GABRA1 P14867 3/20 0.50
GABRB2 P47870 2/20 0.50
TSHR P16473 3/20 0.47
ACHE P22303 2/20 0.47
GABRG2 P18507 2/20 0.46
GABRB3 P28472 2/20 0.46
FAAH O00519 2/20 0.46
SLC6A2 P23975 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
HPGD P15428 1/20 0.46
GABRB1 P18505 1/20 0.46
PTGS1 P23219 1/20 0.46
HTR2C P28335 1/20 0.46
GABRA5 P31644 1/20 0.46
GABRA3 P34903 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5493731 0.97 ESR1 (0.56) ESR1GABRA1GABRB2TSHRACHE
SCHEMBL29392590 0.97 ESR1 (0.56) ESR1GABRA1GABRB2TSHRACHE
SCHEMBL40597 0.97 ESR1 (0.56) ESR1GABRA1GABRB2TSHRACHE
SCHEMBL27612057 0.94 ESR1 (0.54) ESR1GABRA1GABRB2TSHRACHE
Iodide SCHEMBL29230048 0.94 ESR1 (0.54) ESR1GABRA1GABRB2TSHRACHE
Water SCHEMBL3656564 0.94 ESR1 (0.54) ESR1GABRA1GABRB2TSHRACHE
Ammonia Solution, Strong SCHEMBL15769983 0.94 ESR1 (0.54) ESR1GABRA1GABRB2TSHRACHE
Fluoride SCHEMBL28113471 0.94 ESR1 (0.54) ESR1GABRA1GABRB2TSHRACHE
SCHEMBL31498556 0.94 ESR1 (0.54) ESR1GABRA1GABRB2TSHRACHE
Hydrogen Peroxide SCHEMBL10348374 0.92 GABRA1 (0.54) ESR1GABRA1GABRB2TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111499538-B Preparation method of (2S, 3R) -2-acylaminomethyl-3-hydroxybutyrate 南方科技大学 2023-02-17 CN disclosed