Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 4/20 | 1.00 |
| ▸ | MET | P08581 | 13/20 | 0.81 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21478982 | 1.00 | JAK2 (1.00) | JAK2METALK | |
| SCHEMBL21478593 | 1.00 | JAK2 (1.00) | JAK2METALK | |
| SCHEMBL30453123 | 0.94 | JAK2 (0.88) | JAK2METALK | |
| SCHEMBL488360 | 0.94 | JAK2 (0.88) | JAK2METALK | |
| SCHEMBL488269 | 0.89 | MET (1.00) | JAK2METALK | |
| SCHEMBL30453779 | 0.89 | MET (1.00) | JAK2METALK | |
| SCHEMBL5255394 | 0.89 | JAK2 (0.79) | JAK2METALK | |
| SCHEMBL30453067 | 0.88 | MET (0.84) | JAK2METALK | |
| SCHEMBL488641 | 0.88 | MET (0.84) | JAK2METALK | |
| SCHEMBL488237 | 0.88 | MET (0.84) | JAK2METALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112119070-B | Selective JAK2 inhibitors and uses thereof | 华东理工大学 | 2023-02-17 | — | — | CN | disclosed |