Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.73 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.73 |
| ▸ | CYP2A6 | P11509 | 8/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.58 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.55 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.55 |
| ▸ | AXL | P30530 | 1/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2823299 | 1.00 | DYRK1A (0.73) | DYRK1ADYRK1BCYP2A6CYP3A4ALDH1A1 | |
| SCHEMBL29992735 | 1.00 | DYRK1A (0.73) | DYRK1ADYRK1BCYP2A6CYP3A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4832941 | 0.98 | DYRK1A (0.71) | DYRK1ADYRK1BCYP2A6CYP3A4ALDH1A1 | |
| SCHEMBL1256370 | 0.87 | DYRK1A (0.58) | DYRK1ADYRK1BCYP2A6CYP3A4ALDH1A1 | |
| SCHEMBL1257460 | 0.82 | PIK3CD (0.73) | DYRK1ADYRK1BALDH1A1CYP1A2MAP4K4 | |
| SCHEMBL29740321 | 0.82 | PIK3CD (0.73) | DYRK1ADYRK1BALDH1A1CYP1A2MAP4K4 | |
| SCHEMBL10918242 | 0.81 | CYP2A6 (0.65) | DYRK1ADYRK1BCYP2A6CYP3A4ALDH1A1 | |
| SCHEMBL29568613 | 0.80 | MAP4K4 (0.64) | DYRK1ADYRK1BCYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL68829 | 0.80 | MAP4K4 (0.64) | DYRK1ADYRK1BCYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL24534338 | 0.79 | CYP2A6 (0.88) | DYRK1ADYRK1BCYP2A6CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023040998-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-03-23 | — | — | WO | disclosed |
| CN-112119070-B | Selective JAK2 inhibitors and uses thereof | 华东理工大学 | 2023-02-17 | — | — | CN | disclosed |