Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20364262 | 0.79 | ESR1 (0.44) | HDAC1HDAC2ALDH1A1 | |
| SCHEMBL25045623 | 0.76 | HDAC1 (0.36) | HDAC1HDAC2UHRF1 | |
| SCHEMBL16181319 | 0.74 | UHRF1 (0.35) | HDAC1HDAC2UHRF1 | |
| SCHEMBL20038316 | 0.72 | ALDH1A1 (0.49) | ALDH1A1 | |
| SCHEMBL22271499 | 0.71 | DPP9 (0.56) | HSP90AA1NAMPT | |
| SCHEMBL6120302 | 0.71 | HDAC2 (0.49) | HDAC1HDAC2NAMPT | |
| SCHEMBL29690628 | 0.71 | HDAC2 (0.49) | HDAC1HDAC2NAMPT | |
| Hydrochloric Acid SCHEMBL28461524 | 0.70 | HDAC2 (0.48) | HDAC1HDAC2NAMPT | |
| Hydrochloric Acid SCHEMBL28011425 | 0.70 | HDAC2 (0.48) | HDAC1HDAC2NAMPT | |
| SCHEMBL30595328 | 0.70 | DPP9 (0.41) | RYR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848506-B | Biphenyl urea compound and pharmaceutical composition, preparation method and application thereof | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |