Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 11/20 | 0.55 |
| ▸ | KDR | P35968 | 6/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.55 |
| ▸ | BRAF | P15056 | 3/20 | 0.55 |
| ▸ | ARAF | P10398 | 2/20 | 0.55 |
| ▸ | GSK3B | P49841 | 2/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.50 |
| ▸ | TNNI3K | Q59H18 | 3/20 | 0.50 |
| ▸ | PLK4 | O00444 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28943458 | 1.00 | RAF1 (0.55) | RAF1KDRHDAC3HDAC4HDAC1 | |
| SCHEMBL30142968 | 0.92 | RAF1 (0.51) | RAF1KDRHDAC3HDAC4HDAC1 | |
| SCHEMBL28963967 | 0.92 | RAF1 (0.51) | RAF1KDRHDAC3HDAC4HDAC1 | |
| SCHEMBL28963973 | 0.91 | RAF1 (0.70) | RAF1KDRHDAC3HDAC4HDAC1 | |
| SCHEMBL28943449 | 0.91 | RAF1 (0.70) | RAF1KDRHDAC3HDAC4HDAC1 | |
| SCHEMBL28943481 | 0.85 | RAF1 (0.68) | RAF1KDRHDAC3HDAC4HDAC1 | |
| SCHEMBL28943467 | 0.85 | RAF1 (0.68) | RAF1KDRHDAC3HDAC4HDAC1 | |
| SCHEMBL28943521 | 0.84 | RAF1 (0.67) | RAF1KDRHDAC3HDAC4HDAC1 | |
| SCHEMBL28943464 | 0.83 | RAF1 (0.71) | RAF1KDRHDAC3HDAC4HDAC1 | |
| SCHEMBL28943450 | 0.82 | RAF1 (0.66) | RAF1KDRHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848506-B | Biphenyl urea compound and pharmaceutical composition, preparation method and application thereof | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |